International Journal of Medical Research & Health Science. 2017, 6(11): 165-174. ISSN No: 2319-5886.

Osteopathic Manipulative Treatment of Primary Dysmenorrhea and Related Factors: A Randomized Controlled Trial.


Objectives: This study is aimed to evaluate if the osteopathic manipulative treatment (OMT) is effective in patients
with primary dysmenorrhea (PD). Methods: Randomized single-blinded controlled trial with OMT group and lighttouch treatment (LTT) group. Recruited women were 18-40 years (mean age 27 years), with regular menstrual cycle,
normal body mass index (BMI), and a medical diagnosis of PD. Intervention: Patients received five OMT or five
LTT over a menstrual cycle. The primary outcomes were average menstrual pain assessed by the numeric rating
scale (NRS), the duration of pain, and quality of life (QoL) assessed by the SF-12 Short Form Health Survey and
Patient Global Impression Change (PGIC). The secondary outcomes were NSAIDs intake, hours of absence from
school/work, and menstrual-related symptoms. Results: 31 subjects were enrolled, of which five were excluded and
the remaining 26 were randomized. Patients in OMT group had significant improvement in every outcome, including
the average menstrual pain that decreased from 5.35 ± 0.28 to 1.98 ± 0.24 (-63.0%; p<0.001). The mean SF-12
physical component score (PCS) improved from 31.35 ± 1.70 to 49.56 ± 1.92 (+58.1%, p<0.001), the mean SF-12
mental component score (MCS) improved from 38.36 ± 1.16 to 52.04 ± 0.94 (+35.7%; p<0.001). LTT group showed
no improvements. Conclusion: OMT was effective in reducing menstrual pain and improving Quality of Life of
dysmenorrheic women


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